Cambodia is located in the transportation hub of Southeast Asia. Sihanouk Province, located in the south of Cambodia, is one of the windows of Cambodia's opening to the outside world. It has Sihanoukville International Deepwater Port and Sihanoukville International Airport, and its infrastructure conditions are superior.

SSEZ is located in Prey Nob District, Preah Sihanouk Province，about 17 km from the downtown，4 km from the exit of the expressway linking Phnom Penh to Sihanoukville，3 km from Sihanouk International Airport，12 km from Sihanoukville deep seaport, with convenient land, sea and air transportation and obvious location advantages.